| Sunday 14. March 2010 |
| Sporting Lisboa | 3-1 | Guimaraes |
| Valladolid | 1-4 | Real Madrid |
| Toulouse | 1-1 | Marseille |
| AC Milan | 1-0 | Chievo |
| Nacional | 0-1 | Benfica |
| Barcelona | 3-0 | Valencia |
| Galatasaray | 3-0 | Ankaragucu |
| Bayer Leverkusen | 4-2 | Hamburger SV |
| Valenciennes | 0-2 | Rennes |
| Lille | 1-0 | Grenoble |
| Almeria | 1-0 | Malaga |
| Racing Santander | 0-0 | Zaragoza |
| Tenerife | 4-1 | Espanyol |
| Villarreal | 2-0 | Xerez |
| Sunderland | 1-1 | Manchester City |
| Ajax | 4-1 | PSV Eindhoven |
| Asteras Tripolis | 0-1 | Panathinaikos |
| Hoffenheim | 0-1 | Werder Bremen |
| Juventus | 3-3 | Siena |
| Bologna | 1-1 | Sampdoria |
| Livorno | 3-3 | Roma |
| Udinese | 3-2 | Palermo |
| Genoa | 5-3 | Cagliari |
| Lazio | 0-2 | Bari |
| Parma | 1-0 | Atalanta |
| Manchester United | 3-0 | Fulham |
| Bursaspor | 2-0 | Manisaspor |
| CD Guadalajara | 0-0 | Pumas UNAM |
| Pachuca | 0-3 | Santos |
| Tigres | 0-1 | Atlas |
| Banfield | 0-0 | Arsenal S. |
|
| Saturday 13. March 2010 |
| Academica | 1-2 | FC Porto |
| Sevilla | 1-1 | Deportivo La Coruna |
| Lyon | 1-1 | Saint Etienne |
| SSC Napoli | 1-3 | Fiorentina |
| Braga | 1-0 | Rio Ave |
| Gijon | 0-0 | Athletic Bilbao |
| Paris Saint Germain | 4-1 | Sochaux |
| Nancy | 1-3 | Boulogne |
| Montpellier | 1-1 | Auxerre |
| Monaco | 0-0 | Bordeaux |
| Lorient | 1-0 | Lens |
| Le Mans | 0-1 | Nice |
| Hull | 1-2 | Arsenal |
| Bayern Munchen | 2-1 | Freiburg |
| Getafe | 3-0 | Mallorca |
| Genclerbirligi | 0-0 | Fenerbahce |
| Olympiakos | 2-2 | Pas Giannina |
| AEK Athens | 3-0 | Kavala |
| Chelsea | 4-1 | West Ham |
| Burnley | 1-2 | Wolverhampton |
| Bolton | 4-0 | Wigan |
| Birmingham | 2-2 | Everton |
| Stoke | 0-0 | Aston Villa |
| Monchengladbach | 0-4 | Wolfsburg |
| Mainz 05 | 1-0 | FC Koln |
| Hannover 96 | 2-1 | Eintracht Frankfurt |
| Bochum | 1-4 | Borussia Dortmund |
| Hertha Berlin | 1-2 | Nurnberg |
| Tottenham | 3-1 | Blackburn |
| Estudiantes Tecos | 4-1 | Indios de Juarez |
|
| Friday 12. March 2010 |
| Naval | 1-0 | U.Leiria |
| Catania | 3-1 | Inter |
| Schalke 04 | 2-1 | VfB Stuttgart |
| CSKA Moscow | 1-0 | Amkar |
| Dep. Quito | 1-1 | Internacional |
| CD Árabe Unido | 0-1 | Cruz Azul |
| Emelec | 1-2 | Cerro |
| Dep. Italia | 2-2 | Cruzeiro |
|
| Thursday 11. March 2010 |
| Nacional | 0-2 | Sao Paulo |
| Valencia | 1-1 | Werder Bremen |
| Benfica | 1-1 | Marseille |
| Panathinaikos | 1-3 | Standard Liege |
| Juventus | 3-1 | Fulham |
| Hamburger SV | 3-1 | Anderlecht |
| Rubin Kazan | 1-1 | Wolfsburg |
| Atletico Madrid | 0-0 | Sporting Lisboa |
| Lille | 1-0 | Liverpool |
| CSD Comunicaciones | 1-1 | Pachuca |
| CD Marathon | 2-0 | Pumas UNAM |
| Alianza Lima | 2-0 | Juan Aurich |
| Caracas | 1-3 | Flamengo |
| Independiente Medellin | 1-1 | Corinthians |
|
| Monday 08. March 2010 |
| Wigan | 1-0 | Liverpool |
| Valencia | 0-0 | Racing Santander |
| Bielefeld | 0-1 | Karlsruhe |
| Eskisehirspor | 2-1 | Galatasaray |
|
| Saturday 06. March 2010 |
| Real Madrid | 3-2 | Sevilla |
| Roma | 0-0 | AC Milan |
| Almeria | 2-2 | Barcelona |
| Wolverhampton | 0-1 | Manchester United |
| Fiorentina | 1-2 | Juventus |
| Rangers | 3-1 | St. Mirren |
| West Ham | 1-2 | Bolton |
| Arsenal | 3-1 | Burnley |
| Werder Bremen | 2-2 | VfB Stuttgart |
| Freiburg | 1-2 | Hannover 96 |
| Eintracht Frankfurt | 1-4 | Schalke 04 |
| FC Koln | 1-1 | Bayern Munchen |
| Portsmouth | 2-0 | Birmingham |
|
| Friday 05. March 2010 |
|
|
| Wednesday 03. March 2010 |
| Portugal | 2-0 | China |
| Scotland | 1-0 | Czech Republic |
| France | 0-2 | Spain |
| England | 3-1 | Egypt |
| Albania | 1-0 | N.Ireland |
| Italy | 0-0 | Cameroon |
| Belgium | 0-1 | Croatia |
| Germany | 0-1 | Argentina |
| Netherlands | 2-1 | USA |
| Wales | 0-1 | Sweden |
| Slovenia | 4-1 | Qatar |
| Austria | 2-1 | Denmark |
| Poland | 2-0 | Bulgaria |
| Switzerland | 1-3 | Uruguay |
| Romania | 0-2 | Israel |
| Hungary | 1-1 | Russia |
| Algeria | 0-3 | Serbia |
| Turkey | 2-0 | Honduras |
| Bosnia Herzegovina | 2-1 | Ghana |
| Cyprus | 0-0 | Iceland |
| Slovakia | 0-1 | Norway |
| Angola | 1-1 | Latvia |
| Greece | 0-2 | Senegal |
| Georgia | 2-1 | Estonia |
| Ivory Coast | 0-2 | South Korea |
|
| Sunday 28. February 2010 |
| Paris Saint Germain | 0-3 | Marseille |
| Atletico Madrid | 4-1 | Valencia |
| Juventus | 0-2 | Palermo |
| Lille | 1-2 | Auxerre |
| Sevilla | 0-0 | Athletic Bilbao |
| Panionios | 0-2 | Panathinaikos |
| Bayern Munchen | 1-0 | Hamburger SV |
| Xerez | 1-1 | Espanyol |
| Villarreal | 1-0 | Deportivo La Coruna |
| Valladolid | 1-2 | Mallorca |
| Gijon | 3-2 | Osasuna |
| Racing Santander | 0-2 | Almeria |
| Sunderland | 0-0 | Fulham |
| Liverpool | 2-1 | Blackburn |
| Aston Villa | 1-2 | Manchester United |
| Olympiakos | 2-0 | Atromitos |
| Hannover 96 | 0-1 | Wolfsburg |
| AC Milan | 3-1 | Atalanta |
| Genoa | 3-4 | Bologna |
| Chievo | 2-1 | Cagliari |
| Livorno | 1-2 | Siena |
| Udinese | 2-3 | Inter |
| SSC Napoli | 2-2 | Roma |
| Parma | 1-0 | Sampdoria |
| PSV Eindhoven | 5-1 | Waalwijk |
| Groningen | 2-3 | Feyenoord |
| Tottenham | 2-1 | Everton |
| Rangers | 1-0 | Celtic |
| Ajax | 4-0 | Utrecht |
|
| Friday 26. February 2010 |
| U.Leiria | 0-1 | Guimaraes |
| Once Caldas | 2-1 | Sao Paulo |
|
| Wednesday 24. February 2010 |
| Aston Villa | 3-1 | Crystal Palace |
| Tottenham | 4-0 | Bolton |
| Inter | 2-1 | Chelsea |
| Stoke | 3-1 | Manchester City |
| West Bromwich | 2-3 | Reading |
| Fiorentina | 1-2 | AC Milan |
| Udinese | 2-1 | Cagliari |
| CSKA Moscow | 1-1 | Sevilla |
| Al Shabab | 1-1 | Sepahan |
| Mes Krman | 4-2 | Al-Ahli |
| Al-Ain | 0-1 | Pakhtakor Tashkent |
| Al-Sadd | 0-3 | Al Hilal |
| Suwon S.B. | 0-0 | Gamba Osaka |
| Sanfrecce Hiroshima | 0-1 | Shandong Luneng |
| Adelaide United | 1-0 | Pohang Steelers |
| Morelia | 0-0 | Nacional |
|
| Sunday 21. February 2010 |
| FC Porto | 5-1 | Braga |
| Rennes | 1-2 | Lille |
| Real Madrid | 6-2 | Villarreal |
| Bari | 0-2 | AC Milan |
| Almeria | 1-0 | Atletico Madrid |
| Anderlecht | 2-0 | KV Mechelen |
| Besiktas | 1-1 | Galatasaray |
| PAOK Saloniki | 2-1 | Panathinaikos |
| Wolfsburg | 2-1 | Schalke 04 |
| Werder Bremen | 2-2 | Bayer Leverkusen |
| Wigan | 0-3 | Tottenham |
| Sochaux | 0-4 | Lyon |
| Malaga | 2-1 | Espanyol |
| Athletic Bilbao | 4-1 | Tenerife |
| Osasuna | 1-1 | Valladolid |
| Zaragoza | 1-3 | Gijon |
| Marseille | 3-1 | Nancy |
| Manchester City | 0-0 | Liverpool |
| Club Bruges | 2-1 | Standard Liege |
| Fulham | 2-1 | Birmingham |
| AEK Athens | 1-0 | Aris Salonica |
| Freiburg | 0-3 | Hertha Berlin |
| Bristol City | 2-1 | West Bromwich |
| Aston Villa | 5-2 | Burnley |
| Roma | 1-0 | Catania |
| Atalanta | 0-1 | Chievo |
| Bologna | 1-2 | Juventus |
| Palermo | 3-1 | Lazio |
| Siena | 0-0 | SSC Napoli |
| Fiorentina | 2-1 | Livorno |
| Cagliari | 2-0 | Parma |
| PSV Eindhoven | 1-1 | Sparta Rotterdam |
| Ajax | 4-0 | Vitesse |
| Blackburn | 3-0 | Bolton |
| Feyenoord | 2-2 | Den Haag |
| Jaguares | 2-2 | Pachuca |
|
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